Here a little summary about Clubbing in Manhattan... where should I start?!
You can make it in 12 (or even more) hours to 4 (or even more) clubs.
In the afternoon there´s something called a brunch party and, well, it is a brunch that becomes a club after a while. In the early evening you can go out for dinner with club atmosphere and if you´re lucky someone will take you and a group of people in a stretch limo to the following club, otherwise you just take a cab. If you get bored in one club you can (almost) go next door to the next one, that is called "club hopping".
But let me say one thing: If you are planning to have a 12- hour party marathon and earlier in the day you decided to wear your highest and most uncomfortable heels.. take some flat shoes to change with you!!! (I speak from experience)
But altogether: IT IS SO MUCH FUN!